Peak protein from the mutant strain B.1.617.2, also commonly known as the “Delta Variant”. It is a full-length protein, which is active in its native trimeric form, which is stabilized in LMNG detergent.
All viruses undergo rapid mutations and adapt quickly to the countermeasures that the immune system creates against them. The SARS-CoV-2 of the COVID-19 pandemic is no exception here. Peak protein from the mutant strain B.1.617.2, also commonly known as the “Delta Variant”. It is a full-length protein, which is active in its native trimeric form, which is stabilized in LMNG detergent.
Application
ELISA, ligand binding assay (LBA)
objective
This is the peak protein of the mutant strain B.1.617, also commonly known as the “Delta mutant”.
Sequence
Full length sequence (aa 1-1273), 1284 amino acids (including Rho1D4 tag and linker)
Specificity
Mutation that differs from the “parent” SPIKE protein: T19R, Del 157-158, L452R, T478K, D614G, P681R, D950N
Features
All viruses undergo rapid mutations and adapt quickly to the countermeasures that the immune system creates against them. The SARS-CoV-2 of the COVID-19 pandemic is no exception here. During the pandemic, multiple mutant strains emerged.
Purification
Affinity chromatography
Purity
> 98% as delayed by SDS-PAGE