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Interbio aims at setting up a network of technology platforms in order to expand, through collaboration, the existing possibilities within each region. Please find below a list of technology platforms and advanced instrumentation that belong to the Interbio network.
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Valencia UCIM - Affymetrix Microarray Platform
Title : Valencia UCIM - Affymetrix Microarray Platform
Contact Email : ana.barbera@fivec.org
Abstract : Microarray technology for genome and transcriptome analyses. Affymetrix Microarray Platform offers genome-wide expression analysis with Affymetrix GeneChip® Array. We will provide premium service along the full workflow of microarray projects, including advice in experimental design, sample handling and storage, RNA isolation from cells and tissues, sample processing, hybridisation, scanning, data acquisition, data analysis, and data storage.
Description :




This core facility offers Affymetrix microarrays based services for genotyping, gene and miRNA expression.

Multiple Species and custom arrays available.

One array per cassette.

  • Expression Profiling using Whole Genome GeneChips®
  • Expression Profiling using Exon GeneChips®
  • Genotyping and Copy Number Analyses using Whole Genome GeneChips®
  • miRNA profiling using GeneChip® miRNA Array


Affymetrix uses a novel photolithographic and solid phase chemistry to synthesize 25-base long oligonucleotides on its arrays. Each array contains about 1.3 million different oligonucleotides. Each spot on the array contains millions of copies of a single oligonucleotide (each spot is also called a “probe cell”). The generation of a GeneChip array is a multiple step procedure. In the first step of the process, a glass slide with linkers containing photolabile groups is generated. A mask applied to the slide then determines the regions of the slide that will be exposed to ultraviolet light. By applying ultraviolet light the photo-labile protecting groups are removed from the exposed regions of the mask to allow addition of nucleoside phosphoramidites. This step is repeated with different masks, and addition of subsequent nucleoside phosphoramidites based on the sequence of the oligonucleotides being synthesized in a given spot.

3′-based Expression Arrays

A wide range of arrays for over 30 eukaryotic and prokaryotic organisms are available for analysis with 3′–based expression arrays. On these arrays, each gene is represented by a set of 10-12 different oligonucleotide probe pairs. Each probe pair constitutes a perfectly matched and a mismatched probe counterpart that is different at a single base in the center of the probe. This design feature allows the demarcation between signals obtained from specific binding vs. non-specific binding on the arrays. Most of the probes on these expression arrays target unique sequences at the 3’ end of the gene.

Whole Transcript Expression Arrays

Whole Transcript and Alternative Splicing: Exon 1.0 ST Arrays

GeneChip Exon Arrays provide the most comprehensive coverage of the genome and enable two complementary levels of analysis-gene expression and alternative splicing. Multiple probes per exon enable “exon-level” analysis and allow you to distinguish between different isoforms of a gene. This exon-level analysis on a whole-genome scale opens the door to detecting specific alternative splicing events that may play a central role in disease mechanism and etiology. You can also perform “gene-level” analysis, in which multiple probes on different exons are summarized into a single expression value of all transcripts from the same gene, enabling similar analysis workflows to 3'-gene expression.

Whole Transcript: Gene 1.0 ST Arrays

The Gene 1.0 ST Array System offers a cost-effective solution for whole-genome, whole-transcript expression analysis for human, mouse and rat. Each of the well-annotated genes is represented by approximately 26 probes spread across the full length of the gene, providing a more complete and accurate picture of gene expression than 3'-based expression array designs. All 26 probes are automatically summarized into a single expression value per gene, allowing standard analysis software packages and simple analysis workflows to be used to analyze data. Gene 1.0 ST Arrays are the most advanced and cost-effective gene expression profiling option for new microarray users.

Learn more about Affymetrix Array Technologies

We utilize the Affymetrix Integrated GeneChip System featuring the Hybridization Oven 640 , the Fluidics Station 450, the GeneChip Scanner 3000 7G with autoloader, and the Affymetrix GeneChip Operating System (GCOS) Software.



Detection of mutations and polymorphisms.

Estimation of the predisposition of a person having a disease.

Detection of GMO foods.

Morphological differences between tissues.

Classification of tumors and identification of new markers.




Potential Users:


Interns Users from University of Valencia-INCLIVA: Physiology, Biochemistry, Molecular Biology, Genetic Department, Physical-Chemistry, Pathological Anatomy, Preventive Medicine and Pharmaceutical Technology.

Externs Users: Sistemas Genómicos, Hospital General de Valencia, Instituto de Neurociencias de Alicante, Hospital IVO de Valencia, Instituto de Biomedicina de Valencia,Universidad de Granada, Universidad de Sevilla, Biopolis, INIA, and others.





High Throughput Capabilities:


The information derived from these studies of gene expression allows the development of better diagnostic methods, new systems of early research, assessment of genetic predisposition to a particular pathology and development of novel therapeutics to combat various diseases.


State of Development and IPR : under development
Intended collaboration : service contract : full service
Application or research field : Biochemistry
Biomarker identification
Molecular biology
Nucleic acids
Key words technology :

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Toulouse BIOINFORMATICS The Bioinformatics Platform of Toulouse is a core facility opened to public as well as to private researchers. It is a part of the regional life science research platform network, Genopole Toulouse Midi-Pyrénées. The platform is run according to quality management rules and was awarded ISO 9001-2008 certification. The platform provides the users with adapted and powerful material and software infrastructure, training sessions and technical support to bioinformatics projects. The platform offers also preliminary analysis and annotation of sequences generated by Next Generation Sequencing technologies. View information
Toulouse TRI IMAGING Platform The Toulouse TRI Imaging platform is a core facility opened to public as well as to private researchers. It is a part of the regional life science research platform network, Genopole Toulouse Midi-Pyrénées. The platform is run according to quality management rules and was awarded ISO 9001-2008 certification. The platform provides researchers expertise and cutting edge technology in the field of cell imaging. It constitutes a framework for reflexion and exchanges in this currently very rapidly evolving field and contributes to the formation of researchers in all methods related to microscopy. View information
Toulouse PROTEOMICS The Proteomics platform of Toulouse is a core facility opened to public as well as to private researchers. It is a part of the regional life science research platform network, Genopole Toulouse Midi-Pyrénées. The platform is run according to quality management rules and was awarded ISO 9001-2008 certification. The principal aim of the Toulouse Proteomics Platform is to provide state-of-the-art techniques in proteomics to the scientific community. Proteomics is a rapidly expanding field, where instrumentation in mass spectrometry and associated analytical and biochemical strategies are regularly improving. View information
Toulouse METABOLOMIC & FLUXOMIC Platform The Metabolomic & Fluxomic platform of Toulouse METATOUL is a core facility opened to public as well as to private researchers. It is a part of the regional life science research platform network, Genopole Toulouse Midi-Pyrénées. The platform provides large-scale facilities (NMR & MS equipments), tools, and expertise to support research projects that require in-depth investigations of metabolism, its regulation or its engineering, within the fields of microbiology and of human health & food safety. METATOUL supports projects in functional genomics or systems biology with main applications in microbial metabolism, biotechnology, plant-microorganism interactions, microbial pathogenesis and link between metabolism and virulence. View information
Toulouse GENOMICS & TRANSCRIPTOMICS The Genomics and Transcriptomics platform of Toulouse is a core facility opened to public as well as to private researchers. It is a part of the regional life science research platform network, Genopole Toulouse Midi-Pyrénées. The platform is run according to quality management rules and was awarded ISO 9001-2008 certification. It provides state-of–the-art technologies concerning genomic studies and gene expression analysis. Based on its expertise in the field of sequencing and genotyping, the platform gives support to research laboratories for their scientific strategy and technological choice. In particular for Next Generation Sequencing (NGS) data, the information system of the platform provides the users with primary analysis after quality control are performed. View information
Toulouse Integrated Screening Pipeline - PICT The Integrated Screening Pipeline of Toulouse (Plateforme Intégrée de Criblage de Toulouse: PICT) is a multidisciplinary platform which is a part of the regional life science research platform network, Genopole Toulouse Midi-Pyrénées. PICT is aiming at providing the scientific and medical community with a complete package of technologies allowing the identification and the rational design of inhibitors of therapeutic targets, or effectors of any other target, and the characterization of their interactions. Principal applications are in human health, agriculture and environment. View information
Toulouse - The French Plant Genomic Resource Centre - CNRGV CNRGV, the French Plant Genomic Resources Centre (Centre National de Ressources Génomiques Végétales: CNRGV) is responsible for preserving and maintaining plant genomic resources produced in the context of major projects by internationally-renowned laboratories. It is affiliated to the regional life science research platform network, Genopole Toulouse Midi-Pyrénées. The Centre is run according to quality management rules and was awarded ISO 9001-2008 certification. CNRGV is a repository centre for plant genomic libraries and also a service provider dedicated to the scientific community. View information
PRBB_National Institute of Proteomics (ProteoRed) [omp] View information
ICTS_Supercomputing Centre of Catalonia Consortium (CESCA) CONTACT: http://www.cesca.es/en/ Gran Capità, 2-4 (Edifici Nexus) E-08034 Barcelona T. +34 93 205 6464 F. +34 93 205 6979 View information
ICTS_Laboratory RMN Barcelona (RMN) CONTACT: http://www.rmn.ub.es/ Unitat d'RMN Serveis Científicotècnics Universitat de Barcelona C/ Baldiri Reixac, 10 08028 Barcelona Edici Cluster del Parc Científic de Barcelona Tel.+34 93 403 44 66 Fax+34 93 403 44 65 E-mail info@rmn.ub.es View information
ICTS_Clean Room facility of IMB (SBCNM) CONTACT: Instituto de Microelectrónica de Barcelona (IMB) Centro Nacional de Microelectrónica (CNM) Campus UAB 08193 Cerdanyola del Vallès (Bellaterra) Barcelona SPAIN Tel.: +34 93 594 7700 Fax: +34 93 580 1496 e-mail: info@imb-cnm.csic.es View information
ICTS_Barcelona Supercomputing Center (BSC-CNS) CONTACT: Barcelona Supercomputing Center - Centro Nacional de Supercomputación Nexus II Building c/ Jordi Girona, 29 08034 Barcelona (Spain) Phone: (+34) 93 413 77 16 (Switchboard) Fax: (+34) 93 413 77 21 View information
ICTS_Maritime Research and Experimentation Wave Flume (CIEM) CONTACT: Campus Diagonal Nord, Building D1. C. Jordi Girona, 1-3. 08034 Barcelona info.ciemlab@upc.edu View information
ICTS_International Center for Numerical Methods in Engineering (CIMNE) CONTACT CIMNE BARCELONA Edifici C-1, Campus Nord UPC Gran Capitá, s/n 08034 Barcelona, España Tel 34-93 205 70 16 Fax 34-93 401 65 17 View information
ICTS_Synchrotron Light Facility ALBA CONTACT CELLS - ALBA Carretera BP 1413, de Cerdanyola del Vallès a Sant Cugat del Vallès, Km. 3,3 08290 Cerdanyola del Vallès, Barcelona Spain Fax: +34 93 592 43 01 Tel: +34 93 592 43 00 View information
UAB_CBATEG MOUSE CLINIC [abc] View information
UAB_ICN INSTITUT CATALÀ DE NANOTECNOLOGIA (ICN) Campus de la UAB - Facultat de Ciències Edifici CM7 08193 – Bellaterra (Barcelona) Spain Telèfon: + 34 93 581 44 08 Fax: + 34 93 581 44 11 E-Mail: icn@uab.es View information
UAB_CReSA CReSA Edifici CReSA Campus UAB 08193 Bellaterra tel. 93. 581 32 84 fax. 93. 581 44 90 View information
PCB_ChemBioBank CONTACT DETAILS cbb@pcb.ub.cat Tel.+ 34 93 403 4557 www.pcb.ub.cat/chembiobank View information
UAB_Laboratory of Proteomics Laboratori de Proteòmica CSIC/UAB Phone number: +34 93 581 48 55 View information
PCB_ Drug Discovery Plattform Drug Discovery Plattform Parc Científic de Barcelona Campus Diagonal. Universitat de Barcelona C/ Baldiri Reixac, 10-12 08028 Barcelona Tel +34 934 034 557 Fax F +34 934 029 063 drugdiscovery@pcb.ub.cat View information
LISBON - ITQB Research platform on Protein biophysics, structure and dynamics Structural and functional study of biological macromolecules in an integrated research perspective by combining a diversity of multidisciplinar methodologies in macromolecular sciences. View information
LISBON - ITQB/IBET service platform: Analytical services for chemistry and biology Provides certified, GLP compliant, services on analytical development, validation and testing of chemicals and biologicals as well as studies on candidate pharmaceutical products. View information
LISBON - ITQB CERMAX Centre of Magnetic Resonance ITQB hosts the largest Portuguese NMR facility - Centro de Ressonância Magnética António Xavier. CERMAX has several NMR spectrometers (300, 400, 500 and 800 MHz), including the highest field NMR spectrometer in Portugal. This equipment is part of the National NMR Facility. View information
Bordeaux Bioinformatics Center The Bordeaux BioInformatics Centre (CBiB) missions are to federate and stimulate bioinformatics research projects, to satisfy bioinformatics needs related to research activities of biology labs and to be a resource centre to the community by giving WEB access to public services. View information
Bordeaux Genotyping and Sequencing facility The Genotyping and Sequencing facility is part of the Center of functional Genomic Bordeaux (CGFB) and has been labelized by IBiSA and INRA in 2009. View information
Bordeaux IECB Structural Biology Platform (SBP-IECB) SBP-IECB is an interdisciplinary facility at the chemistry and biology interface which aims at answering structural and functional questions on molecules/complexes of biomedical interest with particular emphasis on topics related to biomembranes and gene expression. View information
Bordeaux Imaging Center : BIC The BIC (Bordeaux Imaging Center) offers resources in photonic and electronic imaging, mainly in life, health and plant sciences. View information
Bordeaux Proteomics facility The Plateforme Proteome's goal is to fulfill both academics' and private laboratories' needs in proteomics. We also give acces to our expertise, technics and tools to the entire scientific community. Our facility offer both services, instruments and expertise to the entire scientific community. View information
Valencia UCIM - Animal facilities. We've been dedicated to the humane care and treatment of laboratory animals and the quality research that leads to scientific gains that benefit people. The use of laboratory animals in scientific and medical research is essential to the improvement and protection of the quality of all life. The humane and responsible care of laboratory animals is vital to quality research. View information
Valencia UCIM - Flow Cytometry Unit The Flow Cytometry Unit of the University of Valencia Core Research Facility offers the possibility to perform the classical flow cytometry analysis of the cells in suspension, using Epix elite II (Beckman Coulter) as well as a novel technique of imaging the cells in the flow by a new platform Amnis Imagestream. These two instruments offer the broad range of applications varing from cell cycle analysis, oxidative stress determinations, cell apoptosis detection by classical flow cytoemtry to cell signaling, cell-cell interactions, internalization and autophagy experiments using Amnis Imagestream. Flow core facility is frequented by university researchers as well as collaborators from different research institutions from Valencia and other cities from Spain and abroad. View information
Valencia UCIM - Affymetrix Microarray Platform Microarray technology for genome and transcriptome analyses. Affymetrix Microarray Platform offers genome-wide expression analysis with Affymetrix GeneChip® Array. We will provide premium service along the full workflow of microarray projects, including advice in experimental design, sample handling and storage, RNA isolation from cells and tissues, sample processing, hybridisation, scanning, data acquisition, data analysis, and data storage. View information
Valencia UCIM - Two-dimensional Electrophoresis -The major source of error in a 2-D experiment is gel-to gel variation. To eliminate this , an internal pooled standard should be run on all gels within an experiment. -The same internal standard is run on all gels within an experimental series thereby creating an intrinsic link across all gels. -Normalization of the internal standard across gels allows the ratio of relative expression of the same protein across gels to be compared directly, separating gel-to gel variation from biological variation. -Even small differences in expression levels can be determined by comparing the ratio obtained from one fluorescent-labeled sample directly with another. View information
Valencia FIHGU - Molecular Image laboratory The molecular image service is focussed on the analysis of in vitro and in vivo images which represents a broad catalogue of techniques that are aimed to obtain information from cellular, tissues and animal models. Our equipments are focused in: animal in vivo images with a novel PET-SPECT-CT which allows visualize different animal structures by means of radioactive molecules. Thus, cancer evolution, cerebral metabolism and cardiac function may be monitored over time. In vitro images: precision cut tissue slices to monitor under phase contrast microscope reactivity of perfused arterioles, bronchus, heart and other human or animal structures in a real time fashion by means of a CCD video camera. In vitro diagnostic of primary ciliary dyskinesia by means of ciliary beat frequency. Real time fluorescence images of intracellular calcium, reactive oxygen species, thiol or cAMP levels. Thus, the molecular image service provide a broad service that may satisfy most of the needs of a researcher. View information
Valencia UCIM - SEQUENOM’S platform for Multigenetic Analysis The genetic and epigenetic analysis platform from SEQUENOM is the best technology for the analysis of SNP and CNV variations on DNA samples using Mass spectrometry (MALDI-TOFF). Other applications include quantitative DNA methylation where individual values are given for each one of the CpGs found in a given sequence. Lastly, SEQUENOM’s technology also allows for quick and quantitative determination of gene expression levels bu quantifying the amount of mRNA. View information
Valencia UCIM - Molecular Imaging and Metabolomics Laboratory The principal equipment of this platform is a 600MHz (14T) NMR system, singularly equipped for the automatic and thermostated acquisition at low temperatures of metabolic profiles of biological samples (biofluids, cell lines and tissues), which is essential for the development of metabolomic clinical applications with use in pharmacology studies in different phases. Likewise, the 600MHz NMR equipment has: i) HR-MAS probe for metabolomic studies in tissues and cell lines; ii) NMR microscopy system for imaging, functional and metabolic studies in cells, tissues and animal models; iii) micro-probe (50μL) for dealing with biomedical systems with limited amount of biofluid samples; iv) tetranuclear liquid probe (500μL) for structural studies of biological molecules and complexes. : Bmedical Application II View information
Valencia UCIM - Confocal microscopy A confocal microscope creates sharp images of a specimen that would otherwise appear blurred when viewed with a conventional microscope. This is achieved by excluding most of the light from the specimen that is not from the microscope’s focal plane. The image has less haze and better contrast than that of a conventional microscope and represents a thin cross-section of the specimen. Thus, apart from allowing better observation of fine details it is possible to build three-dimensional (3D) reconstructions of a volume of the specimen by assembling a series of thin slices taken along the vertical axis. View information
FIR-HUVH_Microscopy Leica LMD 6000 microdissection system Features: - High-sensitivity digital camera for fluorescence - Bright field, phase contrast, DIC, polarization and dark field - 1.25x objective - Optimized objectives for microdissection: 5x, 10x, 20x, 40x - 150x objective for chromosomes - Cell recognition program AVC professional - System for living cells microdissection - Optical tweezers View information
PRBB_National Centre of Genotyping (CEGEN) The Spanish National Genotyping Centre (CeGen) was created at the end of the year 2003 by Fundación Genoma España, launched by the Ministry of Health and Consumer Affairs and the Ministry of Education and Science. View information
PRBB_National Institute of Bioinformatics (INB) INB is a technological plattform of Insituto de Salud Carlos III and a future ELIXIR node. A Spanish National Network for coordination, integration and development of Spanish Bioinformatics Resources in genomics and proteomics projects, as well as a help point on translational medicine efforts. View information
PCB_ Automated Crystallography Platform (PAC) The CAP provides the necessary tools, from a volume (250μl) of a sample of purified protein at high concentration (1-10 mg / mL), initiated a process to research the conditions of crystal • glasses. View information
PCB_ Combinatoria Chemistry Platform The Combinatorial Chemistry Unit (UQC-PCB), a Biotechnology Platform that belongs to the Parc Científic de Barcelona (Barcelona Science Park), is equipped with powerful state-of-the-art apparatus. This unit provides research support services to the following sectors: chemical-pharmaceutical, biomedical, biotechnological, and veterinary. In addition, it offers its services to centers and university R+D+I groups and to public research organizations. View information
PCB_Laboratory Animal Applied Research Platform (LAARP) Research involving laboratory animals is centralized in the Animal Research Center (SEA), which is located in the Modular Building of the Parc Científic de Barcelona (PCB). Its services are available to users of the PCB and the Universitat de Barcelona (UB), as well as to researchers from the private sector and other public institutions. View information
PCB_Proteomics Platform MORE INFORMATION View information
PCB_Transcriptomics Platform The Transcriptomics Platform aims to promote the fi eld of gene expression, particularly using biochips, DNA chips and microarrays. The Platform offers the scientific community the technology and know-how necessary for the analysis of samples through DNA microarrays. View information
PCB_Unit of Experimental Toxicology and Ecotoxicology (UTOX-PCB) The Experimental Toxicology and Ecotoxicology Unit (UTOX-PCB), one of the PCB facilities, provides research support to groups and departments of the UB, companies located in the Park, and other public and private research centres. UTOX is part of the Centre de Recerca en Toxicologia (CERETOX). View information
PCB_Nanotechnology Platform The Nanotechnology Platform at Parc Científic Barcelona (PCB) is a 200 m2 laboratory including a 1000/10000 class cleanroom with state-of-the-art micro/nanofabrication and characterization equipment, and consists of a research group, a technology development group, and a service/consulting group. View information
FIR-HUVH_Cytomics The Cytomics Unit offers researchers services of cell sorting, fluorescence activated cell sorting analysis, data analysis and technical and methodological support to carry out cytrometry experiments. View information
FIR-HUVH_Statistics and Bioinformatics Treatment of high throughput data: - Guidance in selecting appropriate statistical tools and methods. - Collaboration in the developingt experimental designs. - Microarray data analysis. - Next generation sequencing (NGS) data analys. - Analysis of other high throughput data typessuch as SNPs, CGH, etc.. For more information go to Statistics & Bioinformatics Unit View information
FIR-HUVH_Metabolomics Equipment - 1 NMR Bruker Avance 400 WB spectrometer, with z-axis gradient with the following probes: - 1 5 mminverse probe 1H-BB - 1 20 mminverse probe 1H-BB - 1 HR-MAS probe 1H-31P-13C - 1 BCUC05 unit to regulate temperature - 1 Equipment Bruker Mini-imaging 0.5 to obtain images - 1 Animal monitoring equipment MORE INFORMATION View information
FIR-HUVH_Proteomics System for two-dimensional electrophoresis of proteins, by Amersham BioSciences, which is composed by two units a pH-gradient strip for isoelectric focusing IPGPHOR, and two electrophoresis units DALT VI for gels of 26 x 20 cm. Scanner and imaging analysis software Image Master Platinum (Amersham BioSciences), for electrophoresis and two-dimensional gels stained with silver or Comassie blue. DIGE System (Differential Gel Electrophoresis, Amersham), for the quantitative analysis of proteins expression profiles based on the fluorescence markup, which is constituted by Typhoon 9400scanner to obtain fluorescence images of two-dimensional electrophoresis gels and the fluorescence images of two-dimensional electrophoresis gels, compatible with conventional stained methods and the fluorescent stained of the system. View information
FIR-HUVH_Molecular Diagnostics Pyrosequencing through the new generation genome sequencer 454 GS FLX by ROCHE, composed by: 1. Fluid system that includes a reactive cassette; a valve collector of 16 positions and a system of peristaltic pumps. 2. Optical system that includes a CCD camera. 3. PC computer (with Linux OS) with the data collection software GS Sequencer v.2.0.0 and the analysis software GS Run Browser. 4. Visual indicator of the instrument's general Status 5. SAI 6. Computation cluster that allows to process a large number of data quickly. View information
IDIBAPS_ Bioinformatics Unit (IDIBAPS) [ABC] View information
IDIBAPS_ Biobank of Hospital Clínic [ABC] View information
IDIBAPS_ Bioinformatics Unit [ABC] View information
FIR-HUVH_Genomics The Automatic Sequencing Service of the STSU offers DNA sequencing based on two different technologies: Sanger technology, through ABI PRISM 3100 Genetic analyzer by Applied Biosystems, Composed by: 1. Automatic arm for plaques of 96 and 384 wells. 2. Detection unit with CCD camera and virtual filters of separation of emitted light. 3. Optical unit with ionic laser of an Ar emission of 488 and 514 nm. 4. PC Pentium® computer with data collection software such as Collection v1.1, GeneMapper v3.0 and SeqScape 2.0, as well as the analysis software Sequencing Analysis v3.7 and GeneScan MORE INFORMATION View information
UAB_CRAG The Center for Research in Agricultural Genomics (CRAG) is a public consortium, with a legal personality that incorporates among its research groups the Consejo Superior de Investigaciones Científicas (CSIC), the Institut de Recerca i Tecnologia Agroalimentàries (IRTA) and the Universidad Autónoma de Barcelona (UAB) as well as other researchers hired by the CRAG or other institutions as ICREA, all of them devoted to the study of genomics and genetics of plants and farm animals. View information
IDIBAPS_Proteomics Unit [ABC] View information
IDIBAPS_ Genomics Unit [ABC] View information
IDIBAPS_ Cytomics Unit [ABC] View information
VALENCIA - UNIT OF CELL PRODUCTION - HEALTH RESEARCH INSTITUTE LA FE (HOSPITAL LA FE) This unit is equipped with isolations and cell manipulation rooms under GMP (Good Manufacture Practices) conditions accredited by the Spanish Drug Agency, where the following takes place: - Isolation of hepatocytes and other human cells. - Cell cryopreservation and storage. - Functional characterization of cells (viability, ureogenic capacity, cytochrome P450 isoenzyme activity, conjugation activity, etc.). - Administrative management of documentation. - Donor and tissue registry of data in computerized database. - Control and registry of stored and used samples View information
VALENCIA - GENOTYPING, GENIC EXPRESSION AND MOLECULAR ALTERATION - HOSPITAL LA FE This platform is aimed at supporting researchers, by means of high-tech equipment. View information
Genomics @ CIPF Valencia The CIPF's Genomics Service has been set up with the purpose of facilitating the access to Sequencing and Microarray technology to companies, research centres, universities and hospitals. View information
Proteomics @ CIPF Valencia CIPF View information
CRG_Bioinformatics Unit Guglielmo Roma Head of the Bioinformatics Unit CRG-Centre for Genomic Regulation Room L439.03 Tel. +34 93 316 01 81 View information
Valencia Biobank La Fe Coordinating Centre of the Biobank Network of Valencia, it has one of the numerically most important collections nationwide of steatosic livers, human hepatic cells, DNA and microsomal samples of normal and pathological tissue. Moreover, it has the most extensive and complete serum bank of patients with coeliac disease in the European Community. Is a national reference for studies of Minimal Residual Disease in neuroblastoma, project coordinator for the creation of the European neuroblastic biobank and hosts the rare disease Biobank set-up by the CIBER-ER. Custody of collections of biological samples linked to data (epidemiological, clinical, genetic, environmental, donor´s habits, etc.) that are relevant to biomedical research. Works under Standard Operating Procedures for reception, storage and transfer of biological samples. Contact person CERVERA ZAMORA JOSE VICENTE (cervera_jos@gva.es) View information
Valencia FIHGU - Pharmacogenetic-pharmacokinetic laboratory Pharmacogenetic research is a promising field of pharmacology which aims to achieve individualized medicine. In this regard there are several examples that are being used currently such as KRAS mutations and cetuximab efficacy, IL28b and peginterferon-γ efficacy, CYP3A5 and tacrolimus pharmacokinetic, CYP2C19 and voriconazol or clopidogrel pharmacokinetic..etc. Thus, pharmacogenetic laboratory has an equipment of DNA and RNA analyzers which allows to detect several single polymorphisms mutations, copy number, deletions, insertions and a variety of DNA-RNA abnormalities which are related with a change of response/toxicity of several drugs. Pharmacokinetic laboratory is closely related with pharmacogenetic since several mutations that affect metabolizing enzyme may affect drug concentrations in human samples. Therefore, we are provided of HPLC equipments with multiple detectors and mass spectrometry to detect variations of drug in biological samples. View information
Valencia-Protein crystallography unit - Instituto de Biomedicina de Valencia We have a service of robotized crystal growth. The service is ntramural, but it can be extended to external projects on a collaborative basis, by agreement with one of the senior staff scientists connected to crystallography (either Alberto Marina, Jerónimo Bravo or Vicente Rubio) View information
Valencia-Yeast two-hybrid analysis Instituto de Biomedicina de Valencia Genetic method for the analysis of protein-protein interactions View information
Valencia-Molecular Imaging System for the detection, image capture and quantitation of fluorescent, luminiscent and radioactive tags on biological samples (on gels, filters, membranes or microtiter/multiwell plates) Instituto de Biomedicina de Valencia The system is composed of a FUJI FLA5000 laser scanner, a LI-COR Odyssey near-infrared laser scanner, a FUJI LAS 3000 and a GE-Life Sciences LAS4000 mini luminescent CCD capture systems. The system is ready to detect and quantify fluorescent signals (i.e. FITC, SYBR green I and II, SYPRO ruby, orange, red and tangerine, FAM, Ethidium bromide, RITC, Cy3, Cy5, TAMRA ROX, HEX, AlexaFluor488, 532, 546, 633,and 680, IRDye680, and 780, DyLight680 and 800, etc.), chemiluminiscent/chemifluorescent signals (ECL, ECL Plus, Lumi-Phos, CDP-Star and similars), radioactive signals (through IP capture screen: 32P, 33P, 35S, 125I, 14C, 3H). View information
Valencia-Human Disease Modelling in C. elegans (HDMCE) Instituto de Biomedicina de Valencia The HDMCE facility is addressed to generate animal models of human genetic disease using the technology of RNA interference /RNAi) in the nematode C. elegans. RNAi is performed by either dsRNA microinjection or feeding. The facilty offers the microscope microinjection system and molecular cloning tools specific for C. elegans experiments. View information
Valencia- Animal genetic manipulation Instituto de Biomedicina de Valencia The Geneticaly modified animals facility offers state-of-the-art technology for the manipulation of the mouse genome. It is a combined facility for both gene targeting in embryonic stem (ES) cells and mouse transgenesis. We are responsible for the cryopreservation of genetically modified mouse strains through embryo freezing and we plans the re-derivation of mouse lines The Unit also provides support to IBV Groups with projects involving mouse models, ES cells and embryos. View information
Valencia-Massive parallel sequencing/Next Generation Sequencing Instituto de Biomedicina de Valencia Equipment SOLiD4 (Applied Biosystems) GS Junior (Roche) Pyromark MD (Biotage/Qiagen) ABIPrism 3130XL (Applied Biosystems) · Applications Genetic analysis of nucleic acids: Resequencing, targeted resequencing, transcriptome analysis, ChIP seq, RNA seq, Sanger sequencing of DNA Methylation analysis SNP detection and analysis Metagenomics · Potential Users Academic and industrial users interested in genetically characterizing products/samples of interest. Potential fields of interest include biomedicina, agriculture, microbiology. · Website http://www.ibv.csic.es http://adn.ibv.csic.es · High Throughput Capabilities Sequencing of up to 60GB in 15 days. View information
Valencia-Drosophila genetics and modeling Instituto de Biomedicina de Valencia At the IBV-CSIC there are facilities to work with Drosophila melanogaster, including rearing, genetics, histology, and microscopy. The research group is led by Dr. Galindo, who has long experience in several aspects of basic and biomedical research using this model organism. Current projects are the regulation of cell signaling by cell polarity and the study of mitochondrial dynamics in peripheral neuropathies. Collaborations could be established when another partner could envisage a utility to develop a Drosophila model, taking advantage of the features of this organism: advanced genetic analysis, transgenics, and high-throughput functional studies. The main application would be the study of biomedical questions (gene function, pathophysiology), but basic research and biotechnological applications can also be explored. View information
Valencia-Proteomics facility Instituto de Biomedicina de Valencia The Proteomics facility at the IBV offers the opportunity to identify individual protein components in complex samples. In this way, it allows the characterization of the proteome of a particular sample. Additionally, our facility is also prepared to sequence the N-terminal part of isolated protein in order to allow its identification. View information
Valencia-Microscopy Facility Service Instituto de Biomedicina de Valencia The Microscopy Facility offers services of light transmission microscopy, inverted microscopy, both incorporating immunofluorescence, and confocal spectral microscopy. The confocal microscopy system has 6 lased lines and 4 laser detectors. It is possible to apply CO2 and temperature control to work with live cells, and there is the option to perform FRET, FRAP and FLIP experiments. The inverted microscope has a digital camera, epifluorescence, and DIC The transmission light microscope is equipped with two digital cameras, light field, dark field, DIC and epifluorescence. There are also software programs for imaging analysis. View information
Valencia-CECT - Colección española de Cultivos Tipo The CECT, Spanish Type Culture Collection, is the only collection of microorganisms that is official and of public nature in Spain, which maintains and supplies bacteria, filamentous fungi and yeasts. Since1991 it is one of the services of the University of Valencia, and presently it acts as the first BRC (Biological research Centre) for microorganisms in Spain (http://www.oecd.org/dataoecd/26/19/31685725.pdf) An on-line catalogue is available on the web (www.cect.org) with detailed information about its holdings, services and activities. The transfer conditions of the microorganisms deposited and supplied are regulated by a ‘Material Transfer Agreement’ (MTA) that follows the recommendations of the Convention for Biological Diversity. It is a member of: - The World Federation on Culture Collections (WFCC) since 1977 (http://wdcm.nig.ac.jp/wfcc) - The European Culture Collection Organization (ECCO) since 1983 (www.eccosite.org). In 1992 it gained recognition as an International Depository Authority (IDA) for storing microorganisms for patent purposes in accordance with the Budapest Treaty (http://www.wipo.int/treaties/es/registration/budapest/index.html). Since 2004 it has been certified by the ISO 9001:2000 System of Quality Control for the ‘Preparation, sale and distribution of microorganisms: bacteria, yeasts and filamentous fungi’ and since 2008 by the ISO 9001:2008. View information
Valencia SCSIE - Central Service for the Support of Experimental Research University of Valencia SCSIE is a general service of technology resources whose mission is to provide centralized and comprehensive support for research carried out in the university community, businesses, and public and private institutions. It is directly managed by the University of Valencia and is functionally dependent on the Office of Research and Scientific Policy. The central unit of SCSIE was created in 1993 on the Burjassot Campus and also has facilities in the Faculty of Medicine (Medical Research Central Unit, UCIM) and at the University of Valencia Science Park. In order to provide top quality service, the SCSIE has an advanced infrastructure of equipment and the best technical personnel, specialized in each area. SCSIE is organized into 14 sections that include the following scientific and technical services for application to different areas of research, healthcare and industry: nuclear magnetic resonance, x-rays, mass spectrometry, atomic spectroscopy, optical and electronic microscopy, genomics, proteomics, bioinformatics, glass blowing, cell cultures, aquariums, animal production, greenhouses, and environmental radioactivity. SCSIE’s aims are, among others, to solve problems concerning the characterization and analysis of raw materials; structural determination of substances and of organic and inorganic compounds; morphological studies of all types of inorganic and biological materials by high-resolution electron microscopy scanning and transmission and confocal microscopy; environmental impact assessment; determination of indices of total α/β in air, water, soil and sediment; nucleic acid sequencing; analysis of food products; detection of transgenic material; diagnosis of hereditary diseases; animal and plant gene identification; forensic genetic testing; etc. SCSIE technology platforms provide support for the following industries; chemical, ceramic, plastic, textile, pharmaceutical, biomedical, clinical, etc., based mainly in Valencia. In addition to providing services, SCSIE provides technical advice and actively participates in technology development projects and research, both nationally and internationally. View information
VALENCIA - ANALYTIC UNIT - HOSPITAL LA FE Equipped with triple quadrupole mass spectrometer (TQ) and Q-TOF-, to support bioanalytical research developed by IIS La Fe, as well as R&D projects of the pharmaceutical, chemical and cosmetic inductry. This Unit is accredited in accordance with the highest international quality standards, ISO 9001 and Good Laboratory Practices (GLP), making the Hospital La Fe the first Medical Centre in Spain with a Bioanalytical unit certified according to said international quality standards. View information
ITQB’s Mass Spectrometry Platform ITQB’s Mass Spectrometry Platform View information
Bordeaux Metabolome Platform ♦ Bordeaux Metabolome Platform of the Center of Functional Genomic Bordeaux (CGFB) has gained the “IBiSA” and “INRA Strategic Platform” labels at national level, and is aimed at meeting the requirements in metabolomics of public or private research groups. ♦ The platform provides services, access to equipments and expertise to the community. ♦The services or collaborations include the acquisition and interpretation of metabolomic or lipidomic profiles, the identification and/or analysis of metabolites (NMR and MS), the measurement of isotopic enrichments. The other platform activities are dedicated to training and technological developments. View information
The Valencian Biobanking Network Services Platforms The Valencian Biobanking Network (VBN), promoted by the Directorate General of Health through the Centre for Public Health Research (CSISP), has been created as an initiative of cooperation and coordination between authorized biobanks in the Region of Valencia. One of the main objectives of VBN is to identify and develop a mass of biological samples of interest for researchers and to increase the accessibility to biological samples by research groups. The network also offers four service platforms to support research to strengthen biomedical research excellence in the Region of Valencia: 1. Hosting and treatment of biological samples service platform; 2. Immunohistological studies service platform; 3. Genetic studies service platform; 4. Studies of high-performance service platform. :http://www.csisp.gva.es/web/biobanco/redvalencianabiobancos View information
The Valencian Biobanking Network Services Platforms The Valencian Biobanking Network (VBN), promoted by the Directorate General of Health through the Centre for Public Health Research (CSISP), has been created as an initiative of cooperation and coordination between authorized biobanks in the Region of Valencia. One of the main objectives of VBN is to identify and develop a mass of biological samples of interest for researchers and to increase the accessibility to biological samples by research groups. The network also offers four service platforms to support research to strengthen biomedical research excellence in the Region of Valencia: 1. Hosting and treatment of biological samples service platform; 2. Immunohistological studies service platform; 3. Genetic studies service platform; 4. Studies of high-performance service platform. :http://www.csisp.gva.es/web/biobanco/redvalencianabiobancos View information

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