This symposium will deal with Nitric oxide-cyclic GMP signal transduction, with special reference to the brain.
The following aspects will be covered in the Symposium:
Molecular components and modulation of the system:
-Nitric oxide and its metabolites (nitrites)
-soluble guanylate cyclase,
-phosphodiesterases,
Roles of nitric oxide-cGMP in:
-Regulation of cerebral blood flow
-Modulation of synaptic plasticity
-Learning and memory
-Circadian rhythms
-Stem cells differentiation
The NO-cGMP system in pathological situations. Therapeutic implications in:
-Ischemia – stroke
-Hepatic encephalopathy
-Alzheimer’s disease
-Depression
Website: http://www.fundacioncac.es/eng/fundacion/actividades/programa.jsp?idActividad=107